“For the five detected intracellular metabolites, the ADC exhibits a significant increase when isoflurane dose varies from 1% to 2%: 13%±8% for myo-inositol, 14%±13% for total N-acetyl-aspartate, 20%±18% for glutamate, 27%±7% for total creatine and 53%±17% for total choline.”