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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Creatine
drug:
Cyclosporine
Research Papers that Mention the Interaction
“Although CsA treatment did not affect theK m (20–24 μm) for creatine, it significantly decreased the V max of creatine uptake in both oocytes and muscle cells.”
“Taken together, our results suggest that CsA inhibited creatine uptake by altering the surface abundance of the creatine transporter.”
“The immunosuppressive drug cyclosporin A CsA ) inhibited the hCRT-1 cDNA-induced creatine uptake inXenopus oocytes and the endogenous creatine uptake in cultured C2C12 muscle cells in a dose- and time-dependent manner.”
Cyclosporin A Inhibits Creatine Uptake by Altering Surface Expression of the Creatine Transporter*
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