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Last Updated: 2 months ago

Possible Interaction: Creatine and Creatinine

supplement:

Creatine

Research Papers that Mention the Interaction

Although the levels of creatine in each formulation were not determined, a substantial conversion of creatine into creatinine has been reported in many formulations and may explain the present findings.
Journal of strength and conditioning research  •  2004  |  View Paper
Creatine supplementation resulted in greater cyst growth and worsened renal function in the Han:SPRD-cy rat, evidenced by greater kidney weights (2.87 ± 0.…; P = 0.0167) and serum urea concentrations (23.96 ± 0.92 versus 20.65 ± 1.06 mmol/L; P = 0.0230), and lower creatinine …).
American journal of kidney diseases : the official journal of the National Kidney Foundation  •  2001  |  View Paper
Food creatine concentration was 5- to 12 -fold greater than creatinine ; food creatine and creatinine were increased 4- and 10-fold, respectively, in the high beef diet compared with the control diets.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1979  |  View Paper
In serum, creatine was found to contribute to creatinine up to 20% when measured by the present GC-MS method.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences  •  2010  |  View Paper
Urinary excretions of guanidinoacetate and creatine correlated positively with creatinine clearance.
Pediatric Research  •  2008  |  View Paper
Urine creatine/creatinine ratio was increased and creatine uptake in fibroblasts was impaired in both patients.
Journal of Inherited Metabolic Disease  •  2006  |  View Paper
Because creatine is converted to creatinine in the body, supplementation with large doses of creatine may falsely elevate creatinine concentrations.
The Annals of pharmacotherapy  •  2005  |  View Paper
Since creatine supplementation may increase creatinine levels, it may act as a false indicator of renal dysfunction.
Journal of herbal pharmacotherapy  •  2004  |  View Paper
Studies on solutions containing creatine and creatinine in various proportions show that in the presence of an excess of creatinine a considerable fraction of the creatine content escapes conversion.
Clinica chimica acta; international journal of clinical chemistry  •  1961  |  View Paper
In connexion with this last postulate Beardw states that the ingestion of creatinine in rats and man greatly stimulates the formation of creatine and creatinine.
The Medical journal of Australia  •  1947  |  View Paper
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