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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Corticosterone
supplement:
Alpha-Ketoglutarate
Research Papers that Mention the Interaction
“When malate, alpha-ketoglutarate or pyruvate was used as a respiration substrate, corticosterone at > or =100 nM decreased ATP production by 10%.”
Direct effects of corticosterone on ATP production by mitochondria from immortalized hypothalamic GT1-7 neurons“ Corticosterone 100 μg/ml inhibited respiration in “coupled” adrenal mitochondria in the presence of 5 mM ketoglutarate but not with 5 mM succinate, suggesting a block at the DPNH oxidase site.”
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