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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ VCE prevents the smoke and X-ray-induced selenium, zinc, magnesium, and copper decrease to strengthen the antioxidant trace element levels in the serum of the technicians.”
“The presence of trace amounts (>75 ppb) of copper enhanced oxidative effects of ascorbic acid , whereas other tested metals did not comparably promote oxidation.”
“Under the cell-free condition, copper is known to oxidize ascorbic acid (the active form of vitamin C) and the event leads to the loss of vitamin C. However, the biological consequence of this interaction was never examined in the presence of cells.”
“High intakes of ascorbic acid and zinc may provide protection against Cu toxicity by preventing excess Cu uptake.”
“ Ascorbic acid is known to inhibit the absorption of copper.”
Copper absorption as affected by supplemental calcium, magnesium, manganese, selenium and potassium.“ Ascorbic acid incubation markedly enhanced the occurrence of copper acetate-induced increases in METHB and decreases in GSH in the sheep and humans.”
“However, ascorbic acid incubation reduced the occurrence of copper acetate-induced increases in METHB, while not effecting changes in GSH in rats.”
“Abstract Based on the occurrence of inherently high levels of erythrocyte copper … sickle cell trait or sickle cell anemia and the demonstrated capacity of ascorbic acid to markedly … of copper , it is proposed that persons with these hereditary blood disorders …-doses of ascorbic acid may experience enhanced hemolytic changes.”
“CONCLUSIONS: The clinical and nutritional status as well as intake of nutrients with antioxidant properties ( u, Zn, Mn, v itamin C and ω3) appears to modulate the variation of NO in this population.”
“For example, vitamin C effectively inhibits lipid and protein oxidation in human plasma exposed to various (patho)physiologically relevant types of oxidative stress, such as activated polymorphonuclear leukocytes, reagent or myeloperoxidase-derived hypochlorous acid, cigarette smoke, or redox-active iron or copper ions (1,3).”
“Potential interactions of RSNOs include that with ascorbic acid (vitamin C), which enhances the ability of copper to catalyse their degradation.”
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