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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Copper and Trientine

supplement:

Copper

Research Papers that Mention the Interaction

The key strategy of treatment is to reduce the amount of copper in the liver and other tissues by administering both copper-chelating agents, such as D-penicillamine or Trientine , and/or zinc acetate.
Rinsho shinkeigaku = Clinical neurology  •  2019  |  View Paper
The mainstay of initial therapy is Cu-chelators like D-Penicillamine, and Trientine for reduction in body copper to sub-toxic levels.
Indian journal of pediatrics  •  2002  |  View Paper
TETA treatment significantly increased the content of Cu in the hypertrophied myocardium, decreased type III collagen deposition and reduced cardiac fibrosis.
Metallomics : integrated biometal science  •  2018  |  View Paper
copper plus … of tetA , while decreasing both the prevalence and gene copies of tetB. In summary, tet gene presence was initially very diverse in the gut bacterial … differentially impacted the prevalence and quantity of the various tetracycline, ceftiofur and copper resistance genes resulting in a less diverse gene population.
Preventive veterinary medicine  •  2015  |  View Paper
Copper supplementation reduced the teratogenicity of TETA ; the reduction was correlated with an increase in maternal and fetal tissue copper levels.
Drug-nutrient interactions  •  1983  |  View Paper
Copper supplementation by a lower dose of TETA suppresses pressure overload-induced cardiac hypertrophy.
Experimental biology and medicine  •  2018  |  View Paper
However, the incubation of copper with TRIEN or EDTA (but not histidine) prior to GSH addition, totally prevented the loss of the original GSH-bleaching capacity.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements  •  2000  |  View Paper