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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Copper and Trientine



Research Papers that Mention the Interaction

The key strategy of treatment is to reduce the amount of copper in the liver and other tissues by administering both copper-chelating agents, such as D-penicillamine or Trientine , and/or zinc acetate.
Rinsho shinkeigaku = Clinical neurology  •  2019  |  View Paper
The mainstay of initial therapy is Cu-chelators like D-Penicillamine, and Trientine for reduction in body copper to sub-toxic levels.
Indian journal of pediatrics  •  2002  |  View Paper
TETA treatment significantly increased the content of Cu in the hypertrophied myocardium, decreased type III collagen deposition and reduced cardiac fibrosis.
Metallomics : integrated biometal science  •  2018  |  View Paper
copper plus … of tetA , while decreasing both the prevalence and gene copies of tetB. In summary, tet gene presence was initially very diverse in the gut bacterial … differentially impacted the prevalence and quantity of the various tetracycline, ceftiofur and copper resistance genes resulting in a less diverse gene population.
Preventive veterinary medicine  •  2015  |  View Paper
Copper supplementation reduced the teratogenicity of TETA ; the reduction was correlated with an increase in maternal and fetal tissue copper levels.
Drug-nutrient interactions  •  1983  |  View Paper
Copper supplementation by a lower dose of TETA suppresses pressure overload-induced cardiac hypertrophy.
Experimental biology and medicine  •  2018  |  View Paper
However, the incubation of copper with TRIEN or EDTA (but not histidine) prior to GSH addition, totally prevented the loss of the original GSH-bleaching capacity.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements  •  2000  |  View Paper