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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Copper
drug:
Streptozocin
Research Papers that Mention the Interaction
“The mean values of Cu were higher (p < 0.05) in liver and kidney samples from STZ as compared to CG.”
Concentration of Zinc, Copper, Iron, Calcium, and Magnesium in the Serum, Tissues, and Urine of Streptozotocin-Induced Mild Diabetic Rat Model“ Cu , Zn, and Vitamin D3 levels were found to increase significantly in STZ groups (p < 0.005).”
“The concentration and the tissue contents of copper in liver and kidney were significantly elevated by 1 wk after STZ injection and increased thereafter, attaining levels two- and fivefold higher, respectively, than controls by 4 wk.”
“The apparent daily absorption of dietary Zn and Cu per 100 g body wt was threefold higher in STZ than C rats.”
“Together, these data demonstrate that increased absorption of dietary Zn and Cu is in part responsible for accumulation of these elements in STZ tissues and suggest altered metal transport at the luminal (brush border) surface of the intestinal epithelium.”
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