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“Results revealed that co-selection occurred rapidly within 6 h. Copper , at the levels of 10 and 100 mg/L, significantly increased bacterial resistance to the antibiotics tested, including rifampin , erythromycin, kanamycin, and a few others.”
“It was found that adsorption of rifampicin on the copper nanosurface enhances its biological activity and prevents the development of resistance.”
“The results obtained indicate that adsorption of rifampicin on the copper nanoparticles surface might provide the reduction of antibiotic dosage and prevent its adverse side effects.”