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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“In severely injured neurons, 30 μM quercetin exerted strong prooxidative action and exacerbated cytotoxic effects of copper , whereas 150 μM quercetin failed to affect neuronal survival.”
PI3K/Akt and ERK1/2 Signalling Are Involved in Quercetin-Mediated Neuroprotection against Copper-Induced Injury“This property of quercetin is distinct from its chemical interaction with copper, but both can contribute to a reduction of copper toxicity.”
“We found that quercetin enhanced metallothoinein induction by copper and the effect was dose dependent.”
“The urate consumption during the incubation of plasma with copper was inhibited by myricetin, quercetin and kaempferol.”
“ Quercetin in a concentration range from 5 to 100 µM decreased manganese superoxide dismutase, glutathione peroxidase, and copper zinc superoxide dismutase mRNA expression levels each by 30–40% in rat hepatoma H4IIE cells.”
The effect of quercetin on the mRNA expression of different antioxidant enzymes in hepatoma cells“Determination of the extent of LDL oxidation by measuring the formation of thiobabituric acid reactive substances (TBARS) after … (10 microM) or 2,2'-azobis (2-amidino-propane) dihydrochloride (AAPH) (5 mM), revealed that glabridin or quercetin consumption … in copper ion induced oxidation, respectively, and a … induced LDL oxidation, respectively.”
“Mannitol produced a small but significant inhibition of the concurrent nuclear DNA damage and lipid peroxidation induced by quercetin in the presence of iron or copper.”
“ Quercetin induced significant (P less than 0.05) concentration-dependent nuclear lipid peroxidation concurrent with DNA degradation; these effects were enhanced by iron and copper ions.”
“Hypothetical mechanisms of reduction of the copper ion by quercetin , stabilization of copper nanoparticles by santin, antimicrobial activity, and reduction of 4-nitrophenol with diagrammatic illustrations are given.”
Green Adeptness in the Synthesis and Stabilization of Copper Nanoparticles: Catalytic, Antibacterial, Cytotoxicity, and Antioxidant Activities“EPR spin trapping experiments have shown that chelation of quercetin to copper significantly suppressed the formation of hydroxyl radicals in the Cu(II)-Fenton reaction.”
“The urate consumption during the incubation of plasma with copper was inhibited by myricetin, quercetin and kaempferol.”
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