Possible Interaction: Copper and Polyphenols

“The present study investigated the influence of melatonin on reactive oxygen species (ROS) generated from polyphenol autoxidation in the presence of copper.”

“We also observed that this reaction was mediated by some polyphenols , especially o-diphenolic-type polyphenols, in the presence of copper ions.”

“The results indicated that high Cu concentration decreased biomass and the content of polyphenols , but elevated electrolyte leakage, while lower Cu concentrations, especially 200 μM Cu, increased the content of polyphenols, EO, and antioxidant capacity in leaves of S. officinalis.”

“ Copper had clear influences on wine polyphenol content.”

“Furthermore, when the copper concentration reached the high ranges (32, 64, and 96 mg/L), the polyphenol content , CIELAB color parameters, and antioxidant activity of wine were substantially decreased, indicating the need to control increasing copper content in grape must.”

“These show that the molecular masses increase with increasing pH, indicating either coordination of increasing numbers of polyphenol molecules as ligands to the copper or the increasing involvement of polyphenol dimers as ligands in the copper coordination sphere.”