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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Copper and Pirenzepine

supplement:

Copper

Research Papers that Mention the Interaction

Cu ,Zn‐SOD (superoxide radical scavenger) 60 000 units/kg, allopurinol (competitive inhibitor of xanthine oxidase) …, dmPGE2 (prostaglandin analogue) 10 μg/kg, cimetidine (H2‐receptor antagonist) 10 mg/kg or pirenzepine (selective antimuscarinic drug) 10 mg/kg all significantly reduced … (800 mg/kg) gastric antral ulcer formation in rats.
Journal of gastroenterology and hepatology  •  1993  |  View Paper
On the other hand, copper slightly decreased the binding affinity of pirenzepine and atropine.
Japanese journal of pharmacology  •  1986  |  View Paper