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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Copper
drug:
Oxytetracycline
Research Papers that Mention the Interaction
“When Zn or Cu was present together with oxytetracycline , there was a strong synergistic effect between the compounds, which increased the selection of ARGs in the collembolan guts.”
Heavy metal-induced co-selection of antibiotic resistance genes in the gut microbiota of collembolans.“This phenomenon might be due to the chelation reaction between oxytetracycline and copper.”
“Combining OTC and Cu led to a higher inhibition of soil microbes than when either chemical was used alone.”
“ OTC alone dramatically inhibited the absorption of Cu by algae, while in the presence of OTC + Cu, only the two high-OTC treatments showed a significant decrease in Cu absorption.”
“The accumulation of OTC in algae was considerably promoted by the addition of Cu , with R increasing 1.5 in T2 to 2.6 in T4; moreover, the residue of OTC in water was reduced in the presence of algae.”
Interaction effects of oxytetracycline and copper at different ratios on marine microalgae Isochrysis galbana.“ Oxytetracycline at 200 µg/ml was not as effective as copper or kasugamycin but significantly reduced the disease as compared with the untreated control.”
“The antibiotic OTC and Cu had significant negative effects on soil microbial community function, particularly when both pollutants were present.”
“The combination of OTC and Cu significantly decreased Shannon's diversity, evenness and utilization of carbohydrates and carboxylic acids compared to individual one of the contaminants.”
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