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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Copper
supplement:
Orotic Acid
Research Papers that Mention the Interaction
“The addition of orotic acid lowered the activities of liver total and Cu ,Zn-superoxide dismutase after feeding for 7, 14, and 21 d. The serum ornithine carbamoyltransferase activity after 14, and 21 d and that of serum alanine aminotransferase after 7, 14, and 21 d were increased.”
Dietary orotic acid increases 1 ,2-diacylglycerol level and lowers superoxide dismutase activity in rat liver.“The addition of orotic acid lowered both the activity of liver Cu , Zn-superoxide dismutase and the level of Cu, Zn-superoxide dismutase mRNA.”
Dietary orotic acid affects antioxidant enzyme mRNA levels and oxidative damage to lipids and proteins in rat liver.
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