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Last Updated: 2 years ago

Possible Interaction: Copper and Norepinephrine

supplement:

Copper

Research Papers that Mention the Interaction

norepinephrine [7.39 +/- 1.18 (Cu) vs. 5.14 +/- 1.06 (C) nmol/l], epinephrine (1.69 +/- 0.33 vs 0.87 +/- 0.16 nmol/….5 +/- 4.7 mU/l), and adrenocorticotropin hormone (11.3 +/- 1.3 vs. 5.5 +/- 0.7 pmol/l) attained higher values in Cu …).
The American journal of physiology  •  1987  |  View Paper
Copper contributes to regulating zebrafish rest–activity cycles through the locus coeruleus system by modulating the biosynthesis of norepinephrine ; brain copper deficiency leads to lower levels of both synaptic norepinephrine and daytime activity.
Nature Chemical Biology  •  2018  |  View Paper
In wildtype mice, Cu supplementation during development caused a significant decline in dopamine and norepinepherine in the midbrain and dopamine in the frontal cortex.
BMC Pharmacology and Toxicology  •  2016  |  View Paper
With doses larger than 3 mg/kg the copper content was higher when measured 30 … of the metal and was depleted to near control values after 6 h. Copper ions in doses of 3, 5 and …/kg increased dopamine and decreased noradrenaline cntents of the hypothalamus … non‐linear fashion.
Acta neurologica Scandinavica  •  1988  |  View Paper
CU 32-085 and bromocriptine reduced the pressor effect of adrenaline, noradrenaline and methoxamine and the hypotensive action of clonidine.
Archives internationales de pharmacodynamie et de therapie  •  1984  |  View Paper
Combined exposure of Mn and Cu also produced a greater elevation in the levels of dopamine (DA) and norepinephrine ( NE ) and a depression of 5-hydroxytryptamine (5-HT) in the brain of animals fed with a 10% casein diet compared to the animals receiving the 21% casein diet.
Chemico-biological interactions  •  1981  |  View Paper
Copper moved the PGI2 dose-response curve against noradrenaline in parallel to the left, suggesting that the two were interacting at some point.
Canadian journal of physiology and pharmacology  •  1979  |  View Paper
Both copper and plastic IUDs markedly reduced the NE content in the uterus, but not in the oviduct, within 1 week after insertion.
Fertility and sterility  •  1975  |  View Paper
In other experiments, Cu 2 + stimulated the rates of autoxidation of dopamine and norepinephrine as well as the neurotoxic agents 6-aminodopamine, 5,6-dihydroxytryptamine and 5,7-dihydroxytryptamine.
Life sciences  •  1978  |  View Paper