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Possible Interaction: Copper and Nitric Oxide



Research Papers that Mention the Interaction

Results: In vitro, copper decreased markedly the survival of neuronal cells and enhanced the production of nitric oxide (NO).
Neurosignals  •  2010  |  View Paper
Conversely, nitric oxide is a potent inhibitor of LDL oxidation when initiated by copper ions or by azo-initiators.
Free radical research  •  1998  |  View Paper
In the presence of copper , the copA mutant exhibited increased sensitivity to killing by nitrite or nitric oxide.
Infection and Immunity  •  2011  |  View Paper
The persistent activation of microglia with the subsequent release of NO vis-á-vis … transition metals such as copper (Cu) in neurodegenerative diseases, prompted the hypothesis that copper … NO signaling by changing the redox environment of the cell and … the fate of NO, microglia would adopt a different phenotype.
Nitric oxide : biology and chemistry  •  2012  |  View Paper
A concomitant increase in the intracellular NO level was observed with increasing concentrations of Cu applied.
Plant & cell physiology  •  2008  |  View Paper
The enzymatic generation of nitric oxide (NO) in vivo has been reported to be modulated by ions, such as copper and iron.
Magnetic resonance imaging  •  2002  |  View Paper
Electrochemical detection of NO showed that the biological effects of ONOO- in HEPES or MOPS were due to accumulation of compounds that released NO in the presence of copper ions.
Free radical biology & medicine  •  1998  |  View Paper
We have previously shown that nitric oxide donors inhibit the oxidation of low density lipoprotein (LDL) initiated by copper ions or by azo-bis-amidinopropane (Hogg et al., 1993.
Journal of lipid research  •  1995  |  View Paper
In addition, Cu exposure markedly changed the levels of glutathione, catalase, and total antioxidant capacity, and upregulated the contents of protein carbonyl, nitric oxide , and malondialdehyde.
Biological trace element research  •  2021  |  View Paper
Additionally, markers of oxidative stress such as catalase, superoxide dismutase, lipid peroxidation products and nitric oxide levels were significantly altered following Cu treatments.
Toxicological research  •  2020  |  View Paper
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