Possible Interaction: Copper and Molybdenum

“The biological antagonism between copper and molybdenum was discovered when cattle grazing pastures high in Mo were found to develop a syndrome characterized by diarrhoea, growth retardation, anaemia and achromotrichia, which could be prevented by administering Cu.”

“Results showed that median concentrations of chromium (Cr), manganese (Mn), cobalt (Co), nickel (Ni), copper Cu), molybdenum (Mo), tin (Sn), barium (Ba), and lead (Pb) in the urine of the case group were significantly higher than those of the control group.”

“CONCLUSIONS Higher co per an d lower mol ybdenum co ncentrations could increase the risk of glucose dysregulation during pregnancy, with women at higher risk of GDM potentially affected to a greater extent.”

“The results obtained suggest that antagonistic interaction between molybdenum and copper might be involved in the progress of diabetes complications.”

“The antagonism between Cu and Mo which had been previously demonstrated in the fetal liver was not found in blood.”

“An interesting point seems to be the inverse relation of copper and molybdenum.”

“High levels of Mo and Ca may exacerbate Cu and P deficiencies, respectively.”

“The increase in F level due to Mo addition appears to be offset by supplementation with Cu.”

“ Cu and Mo liver concentration were higher in the animals with molybdenosis.”

“The 15 mg and 30 mg Mo treatments reduced the Cu in the livers significantly by 24% and 42% respectively.”