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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Copper Gluconate
drug:
Irinotecan
Research Papers that Mention the Interaction
“Fourier transformed infrared (FT-IR) spectroscopy indicated a strengthening of the hydrogen bonds involving the hydroxyl groups when solutions of irinotecan and copper gluconate/TEA are mixed at a 1:1 molar ratio.”
“Spectroscopic analyses revealed that irinotecan interacted with copper gluconate/TEA in solution.”
“The addition of irinotecan to liposomes containing copper gluconate/TEA at 50 degrees C induced a shift of the absorption bands from 370 nm to 378 nm as well as a 60% quenching of the drug fluorescence at 440 nm suggesting the occurrence of irinotecan self association.”
“The intensity of the circular dichroism (CD) signal of copper gluconate/TEA increased in the presence of equimolar amounts of irinotecan.”
Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes.
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