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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Copper
supplement:
Epigallocatechin Gallate
Research Papers that Mention the Interaction
“Thus, GTC , especially ECG and EGCG, seem to inhibit cholesterol oxidation in LDL by combination of interference with PUFA oxidation, the reduction and scavenging of copper ion , hydroxyl radical generated from peroxidation of PUFA and superoxide anion.”
Tea catechins inhibit cholesterol oxidation accompanying oxidation of low density lipoprotein in vitro.“The Cu exposure induced a significant accumulation in the intestine, liver, and gill tissues and the highest accumulation was observed in intestinal tissues (17-34 fold), but dietary EGCG exposure decreased (about 0.8-fold) Cu concentration in each tissue (ANOVA, P<0.05).”
Toxic effects of dietary copper and EGCG on bioaccumulation, antioxidant enzyme and immune response of Korean bullhead, Pseudobagrus fulvidraco.“The fluorescence quenching efficiency of BSA by EGCG was enhanced after EGCG was complexed with copper , and the EGCG-Cu complex exhibited a higher apparent binding affinity (8.88 × 105 M-1) to BSA compared with EGCG alone (5.17 × 105 M-1).”
Interaction between an (-)-epigallocatechin-3-gallate-copper complex and bovine serum albumin: Fluorescence, circular dichroism, HPLC, and docking studies.“On the basis of experimental evidence and theoretical analyses, the mechanism proposed that copper ions played a cooperative role in the bactericidal process of EGCG.”
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