Possible Interaction: Copper and Edetic Acid

“Incubation with EDTA rapidly removes copper bound at the N terminus but is much less effective on the copper ion bound at the active site.”

“Moreover, the solubility of Cu , Zn, and Pb in the gastric phase and gastrointestinal phase were all positively linearly correlated with the results of EDTA.”

“On the other hand, in the presence of 10 mm EDTA , the inhibitory effect of Cu at concentrations up to 2000 nm was abolished (Figure 1).”

“As for the MS, only 2.5–5.0 mmol kg− 1EDTA can elevate the efficiency of Cu , while 5% compost amendment and <5.0 mmol kg− 1 CA application have no marked effects on Cu phytoextraction by E. splendens.”

“The results showed that EDTA application at 2.5–5.0 mmol kg− 1 increased phytoextraction of Cu by four- and eight-fold from both MS and PS, respectively, which is mainly attributed to increased H2O extractable Cu in the soil.”

“Addition of EDTA prevented the modifications found upon copper mediated oxidation of LDL, but EDTA did not prevent the modification of the gas phase cigarette smoke exposed LDL.”

“Concentrations of cupric ions as low as 20 μmol/L severely inhibited apotryptophanase activity and this effect of copper was almost completely prevented by the addition of EDTA.”

“The inhibition of red cell enzymes by copper was completely reversed by the addition of EDTA.”

“The conclusion drawn from this ecotoxicological risk assessment was that EDTA and calcium significantly decreased Cu toxicity in freshwater fish.”

“On the other hand, pyridoxal treatment as well as EDTA treatment increased viability of NM-1 cells treated with homocysteine and copper to about 60%, and significantly decreased extracellular hydrogen peroxide, intracellular ROS and cellular lipid peroxide levels.”

“8 days storage at 50 C. Ethylenediaminetetraacetic acid completely inhibited the effect of copper , as well as iron, under these conditions.”