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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Copper
drug:
Cupric Chloride
Research Papers that Mention the Interaction
“Furthermore, we observed that facilitation of copper uptake by added CuCl2 (2 µM) boosts tonic inhibitory currents.”
Dual Role for Astroglial Copper-Assisted Polyamine Metabolism during Intense Network Activity“Gene silencing of copper transport 1 (CTR1) did not affect cross-membrane transportation of Cu(ii)-TETA, but inhibited copper cellular accumulation from CuCl2.”
“After … of CuCl2 (30 μM) the specific cellular copper content increased from initial 1.5 ± 0.2 nmol/mg to a steady state level of 7.9 ± 0.9 nmol/mg within about 12 h. The copper accumulation was accompanied by a significant increase in the extracellular lactate concentration.”
“Control experiments with CuCl2 suggest the ethiological role of Cu.”
“ICP-MS (Inductively Coupled Plasma Mass Spectrometry) analysis of the cell extracts showed that co-incubation with CuCl2 increases Au and Cu accumulation in both cancer cell lines, in accordance with the enhanced antiproliferative effects.”
Relevance of Copper and Organic Cation Transporters in the Activity and Transport Mechanisms of an Anticancer Cyclometallated Gold(III) Compound in Comparison to Cisplatin
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