Possible Interaction: Copper and Cupric Cation

“While only O-desmethylangolensin mildly chelated iron and copper , all four compounds markedly reduced cupric ions.”

“Conclusion The surface area of the copper and the pH of the test medium modulate the in vitro release of cupric ions from Cu-IUDs.”

“All of these results suggested that burst release of cupric ions could be avoided and the effective utility of copper could be improved in this composite.”

“When the toxicity to spermatozoa of cuprous and cupric ions was compared with copper metal, it could be shown that the quantity of cupric ions required (0.2-0.4 mg/ml) was in excess of the total quantity of copper released into solution.”

“Exposure to copper resulted in increased levels of lipid peroxides in gills (76%) and liver (95–110%) after exposure to 300 and 700 μg L−1 Cu2+.”

“Our data also suggest that the selective inhibition of brain MAO-A by Cu2+ and Cd2+ may assume pathophysiological importance in the neurotoxicity of copper and cadmium.”

“Pre-incubation of mitochondrial membrane preparations with Cu++ increased the copper content and ADP-binding affinity.”

“The effects of copper ions on the binding of steroids to receptors revealed that the inhibitory effect of Cu++ was apparent at 10(-6)M, ANd the binding capacities decreased to 10% at 10(-2)M Cu++.”

“The dissolved oxygen (DO) consumption value in the presence of Cu2+ , CuCO3, CuPRO, and Kocide solutions was significantly influenced by Cu particles/ions.”

“However, under aerobic conditions, Cu exists primarily as Cu(II), and hence Cu(II) reduction is essential for Cu transport/storage.”