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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Copper and Apigenin

supplement:

Copper

supplement:

Apigenin

Research Papers that Mention the Interaction

In conclusion, apigenin could exert neuroprotection against Aβ-induced toxicity in the presence of copper mainly through the mechanisms that regulate redox imbalance, preserve mitochondrial function, inhibit MAPK pathways, and depress neuronal apoptosis.
Our results showed that apigenin protected neurons against Aβ-mediated toxicity induced by copper , which was characterized by increasing neuronal viability and relieving mitochondrial membrane dissipation and neuronal nuclear condensation.
Brain Research  •  2013  |  View Paper
Previous reports from this laboratory have shown that flavonoids including apigenin are capable of inducing oxidative DNA cleavage in the presence of copper ions.
Toxicology in vitro : an international journal published in association with BIBRA  •  2004  |  View Paper