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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Copper and 1-(P-Hydroxybenzyl)-6,7-Dihydroxy-1,2,3,4-Tetrahydroisoquinoline

Research Papers that Mention the Interaction

Cu B combined with higenamine potentiated the cytotoxic effect of Cu B, resulting in the enhanced induction of apoptosis and G2/M arrest.
The associated pathways were summarized by Kyoto Encyclopedia of Genes and Genomes pathway analysis, and it was hypothesized that higenamine may enhance the antitumor effects of Cu B in breast cancer through inhibition of the interaction of AKT and CDK2.
The present study suggested that higenamine enhances Cu B-induced cytotoxicity in breast cancer cells and in vivo.
Oncology reports  •  2018  |  View Paper