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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Conjugated Linoleic Acid
drug:
Interleukin-10
Research Papers that Mention the Interaction
“ CLA supplementation also decreased the levels of the proinflammatory cytokines, TNF-α and IL-1β (P<0.05), but increased the levels of the anti-inflammatory cytokine, IL-10 (P<0.05).”
Effect of CLA supplementation on immune function in young healthy volunteers“ CLA ‐supplementation also increased IL‐10 production in bone marrow‐derived macrophages (143.6±28.6 vs. 94±5.6 pg/ml, n=5; P<0.05).”
“The induction of IL‐10 on CLA supplementation in this model may reflect a systemic alteration toward an anti‐inflammatory phenotype, which, in turn promotes increased vascular infiltration by Ly6Clo monocytes.”
“ CLA enhanced the expression of interleukin-10 (IL-10) and peroxisome proliferator-activated receptor-gamma (PPARgamma) in spleen and thymus.”
Conjugated linoleic acid attenuates the production and gene expression of proinflammatory cytokines in weaned pigs challenged with lipopolysaccharide.
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