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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Colchicine
supplement:
Tretinoin
Research Papers that Mention the Interaction
“Neither Coln nor VCR induced the differentiation of HL-60 cells, but in combination with RA increased the percentage of nitroblue tetrazolium-positive cells, the expression of the mature myelocyte surface marker Mo 1, and the content of MT over the effects produced by RA alone.”
The effects of microtubule disrupting drugs on the differentiation of HL-60 leukemia cells.“ Retinoic acid was also active in this test system; the morphologic transformation was reversed on treatment with colchicine , and intracellular cAMP concentration was elevated approximately 10-fold.”
A rapid and sensitive bioassay involving cultured rat glioma cells to screen for substances capable of elevating intracellular cyclic AMP concentration.
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