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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Colchicine
supplement:
Secretin
Research Papers that Mention the Interaction
“ Secretin levels were upregulated by colchicine , an exemplar of homeostatic stressors, as compared with low constitutive expression in untreated rats.4.”
Secretin: Hypothalamic Distribution and Hypothesized Neuroregulatory Role in Autism“Pretreatment of rats with colchicine (but not with its inactive analog beta-lumicolchicine) inhibited both the increases of AQP1 in the cholangiocyte plasma membrane (94%, P < 0.05) and the bile flow induced by secretin (54%, P < 0.05).”
“Pretreatment of rats with colchicine (but not with its inactive analog β-lumicolchicine) inhibited both the increases of AQP1 in the cholangiocyte plasma membrane (94%, P < 0.05) and the bile flow induced by secretin (54%, P < 0.05).”
Secretin induces the apical insertion of aquaporin-1 water channels in rat cholangiocytes.
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