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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Colchicine
supplement:
Oxytocin
Research Papers that Mention the Interaction
“Preventing cellular transport with colchicine eliminated immunohistochemical staining for oxytocin in the cilia.”
Circadian and light regulation of oxytocin and parvalbumin protein levels in the ciliated ependymal layer of the third ventricle in the C57 mouse“Injection of a low, non-lethal dose of the axonal transport inhibitor colchicine resulted in a rapid and equal accumulation of both NSG and SDG in oxytocin perikarya and of SDG in the abnormal perikarya after one day.”
“Inability of colchicine to suppress oxytocin secretion and synthesis may have been due to the short duration of exposure of luteal tissue to the drug.”
“The hyperpolarization of the secretory cells MP induced with oxytocin and acetylcholine diminishes in its amplitude and duration in presence of colchicine (25 microM).”
“… oxytocin … colchicine while the washout was not affected; the time-course of the 'on and off' of the response to oxytocin was not modified by cytochalasin … aggregates, observed in freeze-fracture studies; after cytochalasin B action the dilation of intercellular spaces classically observed under oxytocin stimulation is strongly reduced.”
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