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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Colchicine and Glycerol



Research Papers that Mention the Interaction

Abstract When mammalian cells are cooled at sub-optimal rates to −196 °C in the presence of the cryoprotectants DMSO and glycerol , pretreatment of the cells with colchicine will significantly enhance the survival of these cells as assayed after thawing.
Cryobiology  •  1978  |  View Paper
Animals treated with colchicine showed marked signs of inner ear malfunction after additional treatment with glycerol , which might indicate that the secretory activity in the sac is closely related to the regulation of inner ear fluid homeostasis and functional disturbance.
Colchicine caused a disturbed secretory activity of the sac induced by glycerol.
Acta oto-laryngologica. Supplementum  •  1991  |  View Paper
These findings indicate that colchicine affects the inner ear fluid regulating mechanisms which may lead to severe functional derangement after additional glycerol treatment.
Treatment with glycerol following pretreatment with colchicine , however, induced marked inner ear dysfunction with impaired sense of balance and audition.
Hearing Research  •  1989  |  View Paper