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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Colchicine
supplement:
Epinephrine
Research Papers that Mention the Interaction
“Pretreatment of the salivary gland pieces with colchicine reduces the secretory response to adrenaline , suggesting an involvement of microtubular proteins in the process.”
The in vitro secretion of epidermal growth factor by mouse submandibular salivary gland“ Epinephrine induces aggregation, a process that is inhibited by colchicine.”
“Although pretreatment with colchicine did not alter basal unstimulated FFA release, mobilization of FFA in the presence of epinephrine or theophylline was reduced.”
“A role for microfilaments and microtubules in the secretion … α-amylase is indicated since cytochalasin B and colchicine inhibited the stimulation of α-amylase release by epinephrine (30 or 15 μM) but only cytochalasin B inhibited the stimulation by N6, O2′ dibutyryl adenosine 3′,5′monophosphate (1.0 mM).”
“Pretreatment of the melanophores in colchicine resulted in a decrease in the rate of melanin aggregation in response to epinephrine.”
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