Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Colchicine and Epinephrine

supplement:

Epinephrine

Research Papers that Mention the Interaction

Pretreatment of the salivary gland pieces with colchicine reduces the secretory response to adrenaline , suggesting an involvement of microtubular proteins in the process.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper
Epinephrine induces aggregation, a process that is inhibited by colchicine.
Endocrine research communications  •  1976  |  View Paper
Although pretreatment with colchicine did not alter basal unstimulated FFA release, mobilization of FFA in the presence of epinephrine or theophylline was reduced.
Journal of lipid research  •  1974  |  View Paper
A role for microfilaments and microtubules in the secretion … α-amylase is indicated since cytochalasin B and colchicine inhibited the stimulation of α-amylase release by epinephrine (30 or 15 μM) but only cytochalasin B inhibited the stimulation by N6, O2′ dibutyryl adenosine 3′,5′monophosphate (1.0 mM).
Biochemical and biophysical research communications  •  1972  |  View Paper
Pretreatment of the melanophores in colchicine resulted in a decrease in the rate of melanin aggregation in response to epinephrine.
The Biological bulletin  •  1969  |  View Paper