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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Cola and Erlotinib

supplement:

Cola

Research Papers that Mention the Interaction

In patients treated with erlotinib and esomeprazole with cola , the mean AUC0-12h increased 39% (range, -12% to 136%; P = .004), whereas in patients not treated with the PPI, the mean AUC0-12h was only slightly higher (9%; range, -10% to +30%; P = .03) after erlotinib intake with cola.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology  •  2016  |  View Paper
Furthermore, our study provides evidence that erlotinib intake with cola does result in higher bioavailability.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology  •  2016  |  View Paper