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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Codeine and Quinine

drug:

Codeine

supplement:

Quinine

Research Papers that Mention the Interaction

Quinine as well as the other inhibitors inhibited both EM and CD O-dealkylation competitively and with small differences in Ki versus EM and CD, respectively.
Quinine was the most potent inhibitor of both these O-dealkylations (Ki = 0.2 microM for both EM and CD , respectively).
Quinine , quinidine, propafenone and sparteine all inhibited EM O-deethylation as well as CD O-demethylation.
Biochemical pharmacology  •  1995  |  View Paper