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Discover Supplement-Drug Interactions

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Last Updated: 4 years ago

Possible Interaction: Cocaine and Varenicline

supplement:

Cocaine

Research Papers that Mention the Interaction

Varenicline dose-dependently reduced responding maintained by nicotine alone (0.0032 mg/kg/inj) (P<0.05), and in combination with cocaine (0.0032 mg/kg/inj) (P<0.05) with no significant effects on food-maintained responding.
Neuropsychopharmacology  •  2014  |  View Paper
In contrast, high-dose varenicline increases reinstatement of cocaine-directed behavior and decreases cocaine SA.
Behavioural pharmacology  •  2010  |  View Paper