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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Cocaine and Tempol

supplement:

Cocaine

drug:

Tempol

Research Papers that Mention the Interaction

Cumulatively, these results suggest that nitroxides such as Tempol can attenuate oxidative damage and cell death induced by cocaine and that PC12 cells can be used as an in vitro model to further investigate the precise molecular mechanism of these compounds.
Furthermore, (3) Tempol significantly inhibited oxidative damage induced by cocaine as reflected by mitochondrial superoxide radical and peroxide enhancement.
European journal of pharmacology  •  2011  |  View Paper
Tempol has a neuro-protective effect against cocaine toxicity in these regions, and it may be beneficial in the treatment of cocaine addiction.
Neuroscience  •  2008  |  View Paper