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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Cocaine and Talc

supplement:

Cocaine

drug:

Talc

Research Papers that Mention the Interaction

Benzoylecgonine formation was significantly reduced, and its t1/2 was significantly prolonged after administration of COC+ALC in the ALC-naive and the ALC-pretreated rats.
In the ALC-naive rats, COC area under the plasma concentration-time curve (AUC) and maximum plasma concentration (Cpmax) were significantly higher after administration of COC+ALC compared with after administration of COC+NS.
Drug metabolism and disposition: the biological fate of chemicals  •  1996  |  View Paper