Possible Interaction: Cocaine and Steroids

“Moreover, cocaine may affect the progesterone levels in women utilizing progesterone-based contraception or steroid replacement treatment after menopause.”

“The first patient continued to use cocaine initially, with improvement in her symptoms only on high doses of steroid.”

“As was found in the initial study, frequency of anabolic steroid use was significantly (P < 0.001) associated with frequency of use in the last 30 days of cocaine , injectable drugs, alcohol, marijuana, cigarettes, and smokeless tobacco.”

“Users of cocaine , topical decongestants, and steroid sprays had a statistically higher rate of Staphylococcus aureus carriage compared to non‐users.”

“Both sex and gonadal steroid hormones may influence the abuse-related behavioral effects of cocaine under some conditions, but there is considerable inconsistency in the literature.”

“OBJECTIVE Determine whether cocaine directly impairs ovarian steroid production and ovulation.”

“Therefore, considering that the administration time of the steroid seems to be an important factor for reducing both cocaine and amphetamine hypermotility, and actinomycin D was able to block the reducing effect of the steroid, our study suggests that DEX exerts its reducing effect through a genomic activation.”

“These findings suggest that in the male rat, the effect of cocaine on the concentration of IR-BE in the AP is modulated by the gonadal steroid environment.”

“The ability of cocaine to inhibit sex steroid incorporation into the hypothalamus during a critical period for sexual differentiation of the brain was examined in females treated at birth with testosterone.”

“This suggests that short-term cocaine exposure affects the follicular steroid milieu, possibly by delaying granulosa cell luteinization.”