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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Finally, as an independent measure of cocaine withdrawal, the potential of exposure to saccharin paired with delayed access to cocaine to produce anxiogenic-like responding in the Light–Dark Emersion test was evaluated.”
“Finally, exposure to saccharin paired with delayed access to cocaine produced anxiogenic-like responding in the Light–Dark Emersion test.”
Conditioned aversive responses produced by delayed, but not immediate, exposure to cocaine and morphine in male Sprague-Dawley rats“Results from the choice phase generally paralleled those from the demand phase, the main finding being that post-session saccharin access caused an increase in cocaine preference.”
“However, as saccharin came to predict cocaine , and elicited aversive taste reactivity, VP responses changed to resemble quinine.”
“In rodents, saccharin consumption is suppressed when the sweet taste stimulus is paired with moderate doses of cocaine.”
“ObjectivesIn female rats, individual differences in saccharin intake during chronic social defeat stress may predict subsequent cocaine self-administration, and may be attributed to alterations in mesolimbic dopamine activity.”
“The results of Experiment 1 demonstrate that C57BL/6J mice, compared with DBA/2J mice, exhibit attenuated suppression of saccharin intake when it is paired with cocaine.”
“In the substitution test, cocaine dose dependently decreased saccharin consumption.”
“Additionally, saccharin score was negatively correlated with the number of days to meet the acquisition criterion for cocaine self-administration, but this was mostly accounted for by the HiS adolescents.”
“Over trials, cocaine and desipramine each dose-dependently suppressed saccharin consumption and did so in an equivalent manner when matched by dose.”
“In contrast, when cocaine followed exposure to saccharin , rates of saccharin consumption decreased over successive saccharin sessions in a dose-related manner in both strains.”
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