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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Cocaine
drug:
Ritanserin
Research Papers that Mention the Interaction
“Cocaine-induced behavioral sensitization after a 7-day withdrawal was significantly reduced with the coadministration of osemozotan, ritanserin or azasetron with cocaine repeatedly for 7 days.”
Effects of osemozotan, ritanserin and azasetron on cocaine-induced behavioral sensitization in mice“These same doses of ritanserin and MDL100907 reduced the hyperactivity induced by cocaine (10 mg/ kg).”
“ RIT has also shown preclinical therapeutic potential for attenuating or blocking lethal and/or toxic effects of exposure to cocaine or the selective 5-HT2 agonist dimethoxyiodophenyl-aminopropane (DOI) in the developing chicken.”
“ Ritanserin pretreatment mitigated the COC induced effects.”
“In combination with cocaine, ketanserin attenuated the discriminative effects of cocaine in most subjects, and ritanserin attenuated the discriminative effects of cocaine in subjects trained at the higher dose.”
“In drug interaction studies, the 5HT uptake inhibitors and quipazine produced an insurmountable attenuation of the behavioral-stimulant effects of cocaine, whereas the 5HT antagonists (ketanserin, mianserin and ritanserin ) with high affinity for 5HT2 binding sites enhanced the behavioral-stimulant effects of low or intermediate doses of cocaine.”
“ Ritanserin , a 5-HT2/1C antagonist, has been suggested to reduce the preference for cocaine in rats.”
“ Ritanserin was bund active against t h m di&rent agents of abuse: alcohol, cocaine , and kntanyl (see FIG.”
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