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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“The profile of action of cocaine was significantly different from that produced by both saline and the lower doses of procaine.”
A comparison of the subjective and cardiovascular effects of cocaine and procaine in humans“ Cocaine was approximately 10-fold more potent than procaine and maintained at maximum significantly more injections and responses than procaine when the ITI was 30 min but not when the ITI was 15 min.”
Comparison of the reinforcing efficacy of cocaine and procaine in rhesus monkeys responding under a progressive-ratio schedule“Seizure susceptibility of procaine and lidocaine increased after the end of two days of treatment with a subconvulsive dose of cocaine.”
“ Procaine (37 mM) in equimolar doses to cocaine , produced a small statistically significant decrement in MABP (P < 0.05) without ventilatory effects.”
“ Procaine (15 mg kg-1) mimicked the effects of cocaine (5 mg kg-1) on blood pressure and renal sympathetic nerve activity.”
“ Procaine was administered as a control for the anesthetic effects of cocaine and caused an initial tachypnea that was similar to that for cocaine.”
“ Procaine (4 mg/kg, icv) produced tachycardia, but the effect was significantly less than that produced by cocaine (4 mg/kg, icv).”
“In addition, the consistent preference for cocaine over procaine in monkeys suggests that the infrequent abuse of procaine by humans may be related to its low reinforcing efficacy relative to drugs such as cocaine.”
“Of outstanding importance is the fact that cocaine , in contradistinction to novocain , has a bactericidal effect on the organism.”
BACTERIUM GRANULOSIS IN RELATION TO TRACHOMA: ITS RECOVERY FROM EXPERIMENTALLY INFECTED MONKEYS AND FROM HUMAN TRACHOMA
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