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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Cocaine and Procainamide

supplement:

Cocaine

Research Papers that Mention the Interaction

PA (42.5 micromol/L) profoundly inhibited degradation of COC by 42.7% and of CE by 47.2%.
Journal of analytical toxicology  •  1999  |  View Paper
Procainamide (PA), a cardioactive drug, inhibited the degradation of both cocaine (COC) and cocaethylene (CE) when either was incubated in human liver homogenates for 3 h at 37 degrees C. PA appeared to enhance the formation of CE when COC and ethanol (ETOH) were incubated together in liver homogenate.
Journal of analytical toxicology  •  1999  |  View Paper