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Last Updated: 4 years ago

Possible Interaction: Cocaine and Pimavanserin

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supplement:

Cocaine

drug:

Pimavanserin

Research Papers that Mention the Interaction

“We also found that baseline impulsive action predicted the effectiveness of pimavanserin to suppress incubated cue reactivity in late abstinence from cocaine self-administration at doses that were ineffective in early abstinence.”

The 5-HT2A Receptor (5-HT2AR) Regulates Impulsive Action and Cocaine Cue Reactivity in Male Sprague-Dawley Rats

The Journal of Pharmacology and Experimental Therapeutics • 2019 | View Paper

“Repeated pimavanserin (3.2 mg/kg per day) treatments significantly increased small unit cocaine dose choice.”

Repeated 7-Day Treatment with the 5-HT2C Agonist Lorcaserin or the 5-HT2A Antagonist Pimavanserin Alone or in Combination Fails to Reduce Cocaine vs Food Choice in Male Rhesus Monkeys

Neuropsychopharmacology • 2017 | View Paper

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