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Last Updated: 2 years ago

Possible Interaction: Cocaine and Phenylephrine

supplement:

Cocaine

Research Papers that Mention the Interaction

Cardiac complication from use of cocaine and phenylephrine in nasal septoplasty.
American journal of therapeutics  •  2018  |  View Paper
This letter is in response to a case reported in theArchivesby Ashchi et al 1 titled, "Cardiac Complication From Use of Cocaine and Phenylephrine in Nasal Septoplasty."
Archives of otolaryngology--head & neck surgery  •  1996  |  View Paper
Cocaine and guanethidine enhanced the motor response to adrenaline, noradrenaline and phenylephrine while the action of dopamine was blocked by these two drugs.
Journal of autonomic pharmacology  •  1981  |  View Paper
Intra-mPFC injection of phenylephrine , an α1 adrenoceptor agonist, before the posttest session without stress exposure significantly enhanced cocaine CPP.
Neuropharmacology  •  2020  |  View Paper
Repeated administration of cocaine affected baroreflex activity and impaired vascular responsiveness to both sodium nitroprusside and phenylephrine.
Journal of cardiovascular pharmacology  •  2012  |  View Paper
Cocaine HCl, 2 x 10(-3) M, was found to inhibit contractions by phenylephrine ; EC50s were increased (P<0.01) and Emax's were decreased (51.3+/-16.4% vs. 89.8+/-10.6%, P<0.01).
European journal of pharmacology  •  2004  |  View Paper
An inhibition of neuronal uptake with cocaine caused a small but significant increase in the potency of (−)-phenylephrine.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper
Reboxetine (10-7 M) and cocaine (10-5-2 × 10-4 M) enhanced the contractions evoked by phenylephrine and norepinephrine.
Journal of Pharmacology and Experimental Therapeutics  •  2003  |  View Paper
In the rat epididymal vas deferens the potency of noradrenaline and phenylephrine was increased in the presence of neuronal and extra-neuronal uptake blockers, cocaine and beta-oestradiol, but these did not alter that of methoxamine.
British journal of pharmacology  •  1995  |  View Paper
Cocaine potentiated the initial fast but not the secondary slow responses to phenylephrine suggesting that neuronal uptake limits the initial fast but not the secondary slow response to phenylephrine.
Journal of autonomic pharmacology  •  1988  |  View Paper
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