supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Cocaine
drug:
Phencyclidine
Research Papers that Mention the Interaction
“These data suggest that the use of phencyclidine may be decreasing, possibly due to increase in abuse of other drugs such as cocaine and the amphetamines and to the more stringent restrictions placed upon phencyclidine synthesis.”
Phencyclidine detection during toxicology testing of a university medical center patient population.“ Cocaine has been adulterated or admixed with numerous substances, among them local anesthetics, amphetamine, phencyclidine , and strychnine.”
“In addition, animals exposed to prenatal cocaine were more sensitive to the enhancing effect of phencyclidine (2.0 mg/kg) on startle responses to an acoustic stimulus.”
Enduring effects of prenatal cocaine administration on emotional behavior in rats“Selected doses of dizocilpine, magnesium chloride, and phencyclidine given in combination with 1 mg/kg cocaine produced more cocaine-appropriate responses than this dose of cocaine alone.”
“After pretreatment with the lowest effective dose of cocaine , which decreased rate without affecting accuracy when given alone, the rate-decreasing and error-increasing effects of phencyclidine were generally even more pronounced in two of three subjects.”
“The results indicate that cocaine potentiates the disruptive effects of phencyclidine on complex operant behavior in monkeys.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback