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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cocaine
drug:
Pentoxifylline
Research Papers that Mention the Interaction
“The synergistic activity of cocaine was reduced by neutralizing antibodies to TNF-alpha and by pentoxifylline , an inhibitor of TNF-alpha mRNA production.”
Cocaine amplifies HIV-1 replication in cytomegalovirus-stimulated peripheral blood mononuclear cell cocultures.“These results suggest that PTX reduces or shortens the reinforcing efficacy of cocaine and heroin, leading to compensatory increases in drug self-administration.”
Inactivation of Gi and G(o) proteins in nucleus accumbens reduces both cocaine and heroin reinforcement
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