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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Cocaine and Pentazocine



Research Papers that Mention the Interaction

In myenteric plexus-longitudinal muscle preparations of isolated guinea pig ileum, 1 microM cocaine enhanced the agonistic effects of both pentazocine and ethylketocyclazocine.
These results indicate that cocaine may potentiate the antinociceptive effects of morphine and pentazocine by acting on the kappa-opioid receptors as an agonist.
Japanese journal of pharmacology  •  1988  |  View Paper