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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Cocaine
drug:
Paroxetine
Research Papers that Mention the Interaction
“Furthermore, paroxetine binding showed a significant negative correlation with most measures of sensation seeking, impulsivity, and aggression--though not craving--among cocaine patients.”
“The Bmax values of paroxetine binding were significantly reduced among cocaine patients compared to controls.”
Relationship between platelet serotonin uptake sites and measures of impulsivity, aggression, and craving among African-American cocaine abusers.“ Cocaine patients had significantly lower Bmax values of paroxetine binding compared to controls.”
“ Paroxetine inhibited the binding with similar affinity as cocaine , in the range 200-300 nM. In the frontal cortex, [3H]WIN 35,428 labelled cocaine- and alaproclate sensitive binding sites, of which a major fraction was of protein nature.”
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