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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cocaine
drug:
Oxymetazoline
Research Papers that Mention the Interaction
“… oxymetazoline application at an interval of 1 h … in about 3 h. Exposure to cocaine (10 μmol/l), hydrocortisone (100 μmol/l) and U-0521, a catechol-O-methyltransferase inhibitor (100 pmol/… 92-, 32- and 7 fold in iris dilator tissue of albino rabbit, pigmented rabbit and human, respectively.”
Comparison of post-junctional α-adrenoceptors in iris dilator muscle of humans, and albino and pigmented rabbits“When the stimulation-induced overflow was large under control conditions (high frequency of stimulation, addition of cocaine ), the inhibitory effect of oxymetazoline was diminished.”
Alpha-receptor-mediated modulation of transmitter release from central noradrenergic neurones
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