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Last Updated: 2 years ago

Possible Interaction: Cocaine and Neuropeptide Y

supplement:

Cocaine

Research Papers that Mention the Interaction

Several lines of evidence suggest a possible involvement of the NPY system in the physiological effects of several classes of abused substances including alcohol, phencyclidine, cocaine , and marijuana and in endogenous psychosis.
Psychiatry and clinical neurosciences  •  2009  |  View Paper
Additional studies suggest that cocaine may affect NPY expression.
Alcoholism, clinical and experimental research  •  2008  |  View Paper
Results revealed that NPY injections augmented cocaine-induced hyperactivity and moderately increased cocaine self-administration.
Peptides  •  2009  |  View Paper
At 15 days, the GnRH IPI was significantly decreased after incubation with cocaine and amphetamine‐regulated transcript (CART), α‐melanocyte‐stimulating hormone, corticotrophin‐releasing factor (CRF) and neuropeptide Y ( NPY).
Journal of neuroendocrinology  •  2007  |  View Paper
However, cocaine produces long-lasting changes in NPY expression that are of unknown functional significance.
Brain Research  •  1993  |  View Paper