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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cocaine
drug:
Nandrolone
Research Papers that Mention the Interaction
“Given that accumbal outflow of DA and 5-HT, as well as LMA and stereotyped behavior are all related to reward of stimulant drugs, this study suggests that nandrolone decanoate has significant, long-lasting but reversible effects on the rewarding properties of cocaine.”
“The increases in extracellular dopamine (DA) and serotonin (5-HT) concentration, as well as stereotyped behavior and locomotor activity (LMA) evoked by cocaine were attenuated by pretreatment with nandrolone.”
Subchronic steroid administration induces long lasting changes in neurochemical and behavioral response to cocaine in rats“ConclusionsGiven that accumbal outflow of DA and 5-HT, as well as LMA and stereotyped behavior, is related to gratification of stimulant drugs, this study suggests that nandrolone , at the doses tested, has a significant effect on the pleasurable properties of cocaine.”
“However, nandrolone pretreatment was found to significantly potentiate the heart rate response to cocaine (45 mg/kg, i.p.)”
“Testicular weights of the cocaine plus nandrolone group were less than those of the control and cocaine groups.”
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