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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Cocaine
drug:
Minocycline
Research Papers that Mention the Interaction
“In WT mice in which minocycline inhibited development of cocaine sensitization, a 4-day cocaine treatment increased GluR1 phosphorylation at both Ser831 and Ser845 sites in the frontal cortex but not the striatum; further, this effect was prevented by minocycline.”
Effects of minocycline on cocaine sensitization and phosphorylation of GluR1 receptors in 5-lipoxygenase deficient mice“In this work, we tested the hypothesis that similar to its effects on methamphetamine-induced locomotor sensitization, minocycline may influence the behavioral effects of cocaine.”
“We found that 80 mg/kg minocycline significantly reduced locomotor activity when administered either alone or injected 30 min prior to cocaine , which increased locomotor activity.”
Minocycline affects cocaine sensitization in mice
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