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Discover Supplement-Drug Interactions

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Possible Interaction: Cocaine and Mianserin

supplement:

Cocaine

Research Papers that Mention the Interaction

In drug interaction studies, the 5HT uptake inhibitors and quipazine produced an insurmountable attenuation of the behavioral-stimulant effects of cocaine, whereas the 5HT antagonists (ketanserin, mianserin and ritanserin) with high affinity for 5HT2 binding sites enhanced the behavioral-stimulant effects of low or intermediate doses of cocaine.
The Journal of pharmacology and experimental therapeutics  •  1995  |  View Paper
Cocaine increased the inhibitory effect of mianserin on the pressor effect caused by electrical stimulation and NA.
General pharmacology  •  1992  |  View Paper